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Common signs and symptoms of tardive dyskinesia

Common signs and symptoms of tardive dyskinesia

Tardive dyskinesia is an uncommon movement disorder caused due to the side effects of treatments for schizophrenia, bipolar disorder, and other mental health conditions. It is marked by a series of involuntary body and facial movements. While not everyone who takes this sort of treatment will suffer from tardive dyskinesia, the symptoms can be permanent. It can prevent people from performing simple tasks and can interfere with their quality of life. The most common signs of tardive dyskinesia are: Orofacial dyskinesia Also called oro-bucco-lingual dyskinesia, this can cause: Uncontrolled movements of the lips, jaw, or tongue Sticking out the tongue involuntarily Rapid blinking Smacking of lips Puckering of lips Puffing of cheeks Grimacing Making fish-like mouth movements Dyskinesia of the limbs This affects the arms, legs, fingers, and toes and can cause: Wiggling of fingers Tapping of feet Flapping of arms Thrusting out of pelvis Full body swaying Fast, jerking motions of arms or legs Slow, twisting motions of arms or legs Those who suffer from tardive dyskinesia (TD) can also develop muscle spasms sometimes, where their muscles tighten and do not release. These spasms could vary in duration. One may also make involuntary grunting noises when their muscles spasm.

Top 7 lesser-known signs of multiple myeloma

Top 7 lesser-known signs of multiple myeloma

Multiple myeloma is a cancer that affects plasma cells in the bone marrow and is often misdiagnosed. While some symptoms like bone pain and fatigue are more widely recognized, there are lesser-known signs of multiple myeloma that may not immediately raise alarm bells. It’s crucial to be aware of these subtle indicators, as early detection can make a significant difference in managing this condition. So, here are 7 lesser-known signs of multiple myeloma. Frequent infections One lesser-known sign of multiple myeloma is an increased susceptibility to infections. Plasma cells play a crucial role in a person’s immune system, and when they are compromised by cancer, one’s body becomes less efficient at fighting off infections. If someone finds themselves falling ill more frequently or experiencing recurrent infections, it could be a sign that their immune system is compromised. Skin changes Multiple myeloma can sometimes lead to skin-related symptoms, including the development of small, red, or purple spots on the skin, known as petechiae. These spots are caused by bleeding under the skin and result from the cancer affecting blood clotting factors. While petechiae can have other causes, their presence, along with other concerning symptoms, should prompt a discussion with a healthcare provider.

Novavax vaccine – Development and deployment stages explained

Novavax vaccine – Development and deployment stages explained

Novavax’s COVID-19 vaccine is known by several names globally, including NVX-CoV2373 and Nuvaxovid in some regions. The vaccine uses a tiny piece of the SARS-CoV-2 virus’s spike protein as its primary antigen. This spike protein is the part of the virus that lets it enter human cells and enhance the body’s immune response. The vaccine further includes an adjuvant called Matrix-M. Here are a few details about the vaccine’s development and deployment. Preclinical development Novavax began developing the vaccine in early 2020 utilizing its nanoparticle technology platform. The company identified a stabilized SARS-CoV-2 spike protein as its antigen and combined it with an adjuvant (Matrix-M) to enhance the immune response. Phase 1 and phase 2 trials Novavax initially conducted clinical trials in two phases to evaluate the vaccine’s safety and immunogenicity. These trials involved a relatively small number of participants and aimed to determine the appropriate dosage. Phase 3 clinical trials In the latter half of 2020 and early 2021, Novavax initiated large-scale phase 3 clinical trials to assess the vaccine’s efficacy in preventing COVID-19. These trials involved thousands of participants in multiple countries. Authorization and approval The Novavax vaccine, like other COVID-19 vaccines, required regulatory authorization or approval by a country’s authorities before it could be used.

6 lifestyle habits that may disrupt menstrual cycle

6 lifestyle habits that may disrupt menstrual cycle

The menstrual cycle is a complex natural process controlled by female hormones and causes regular bleeding (periods). However, this cycle could be interrupted due to several factors, including pregnancy, menopause, or underlying health complications. As a result, the period may occur early or late, along with a difference in the blood flow. But apart from natural factors, one might also make these six lifestyle errors that may affect their menstrual cycle. Stressing out Stress caused by factors, including work, personal issues, or other reasons, could be unhealthy for one’s overall well-being. When an individual is stressed, it may cause problems with the gonadotropin-releasing hormone (GnRH), which helps regulate ovulation and menstruation. So the period may stop or change from its normal pattern. While this may not cause long-term problems, it is recommended to look for ways to reduce stress. For example, one could indulge in yoga, tai-chi, breathing exercises, and other techniques to improve mental well-being. Exercising excessively Regular exercise is one of the best ways to maintain physical and mental health. However, intense routines may apply more stress on the body, which might tamper with the hormones responsible for the period. Therefore, it is important to avoid high-intensity exercises if one’s menstrual cycle is affected.

6 uncomfortable questions to ask a dentist

6 uncomfortable questions to ask a dentist

Dental visits, no matter how unpleasant, are essential to maintain good oral hygiene. Most dental appointments may involve routine checkups and cleanings. At times, however, you may have questions regarding procedures or habits, but any feeling of embarrassment or worry over judgment from the dentist may prevent you from asking them. To make it easier for you, here are some of the most common but uncomfortable questions that people are too shy to ask. Where does the saliva go? You may have seen the suction line during any dental procedure. This suction removes the excess saliva and tooth debris from one’s mouth and helps to keep their mouth dry, which can otherwise interfere with the treatment. The device funnels waste materials, including spit, through a filtering system that separates liquids from solids. The waste is then disposed of into the office’s wastewater system. Does the treatment have any side effects? Filings, extractions, and root canals may have potential risk factors. Some common side effects may include pain, swelling, or temporary sensitivity. By asking about the possible side effects of a treatment to your dentist, you can better prepare for any discomfort or complications that may arise after the procedure. What are the potential dental risks I should be aware of?

7 subtle signs that may indicate schizophrenia

7 subtle signs that may indicate schizophrenia

Schizophrenia is a severe brain disorder where individuals start to perceive reality in different ways. Studies indicate that mental illness affects about 1.1 percent of the adult population in the country. Treatment methods, therapies, and coping mechanisms can help an individual cope with the condition. However, diagnosing the disorder may take time as the symptoms do not surface until later in life. So here are seven subtle symptoms that may indicate the development of schizophrenia. Social withdrawal One of the signs that are easy to miss is social withdrawal. Here the individual may exclude themselves from opportunities for social interactions. The person may not avoid talking to others because they believe no one understands them. The sign may eventually lead to social isolation, where the individual may also avoid talking to friends and family members. Social withdrawal, when left unchecked, may also lead to depression – a symptom of schizophrenia. Outbursts of negative emotions Signs like hostility, extreme reactions to criticisms or jokes, suspiciousness, and impulsivity are signs seen in the general population. But there’s a chance that people with anger issues or those who always doubt others might be experiencing early signs of schizophrenia. Unlike others, an individual in the early stages of schizophrenia may exhibit sudden negative emotions for no apparent reason.

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Black Friday 2023 – Top 10 Smartphone Deals to Watch Out For

Black Friday 2023 – Top 10 Smartphone Deals to Watch Out For

Even during non-festive periods, smartphones sell like hotcakes in online and offline stores. Most tech enthusiasts routinely feel the need to get their hands on the latest models of their favorite smartphones. With Black Friday 2023 still several weeks away, shoppers can check out the features of their favorite smartphones. All the estimated deals listed in this article are based on the existing retail discounts, and buyers can expect similar bargains this Black Friday. High-range smartphones 1. Different variants of Apple’s iPhone make up the top 4 of the bestselling smartphones in the country. On many retail sites, devices such as the Apple iPhone SE 5G are being sold with discounts that range from about $200 to $250. This means that there is a high percentage chance that similar or better deals will likely emerge for such devices when Black Friday looms closer. The Apple iPhone SE 5G offers fantastic features such as lightning-fast processors, 5G connectivity, 4K video recording capability with 60 FPS, the unique Dynamic Island display, IP67 water resistance, and many more. 2. Samsung’s Galaxy devices come second in the sales pecking order after Apple’s iPhones when it comes to the smartphone market leadership. With the presence of Black Friday looming on the horizon, users can expect great deals on their favorite Galaxy smartphones. For instance, the Galaxy Z Fold 5 is available on many retail sites with existing discounts ranging from 10% to 15%. Shoppers may possibly find such (or better) discounts during the upcoming sale period. The Galaxy Z Fold 5 is a one-of-a-kind foldable phone packed with incredible features such as a massive display, dual-app viewing, immersive gaming experience, super AMOLED screens, and many other niceties. 3. A device that is likely to offer massive discounts during Black Friday is the Google Pixel 7.

10 Incredible Black Friday Deals to Expect on Laptops in 2023

10 Incredible Black Friday Deals to Expect on Laptops in 2023

Laptops combine the power of desktops with the portability of smartphones, making them suitable for several tasks. But this is also why they tend to be pricey. Unsurprisingly, many wait for sales like Black Friday to buy the model of their choice. Below are ten types of laptops and the Black Friday 2023 deals one can expect on them in the coming months. The discounts listed are based on last year’s sale and current prices. 1. Dual-screen laptops Unlike older dual-screen models, newer ones are much more efficient and non-gimmicky. They have secondary displays with anti-glare capability that perfectly complement the primary screen. A great option is the ASUS Zenbook Pro Duo UX581. It comes with a 15.6-inch 4K UHD NanoEdge touchscreen glossy main display, a cutting-edge Intel Core i7-9750H Quad Core Processor, and a 14-inch 4K matte touchscreen for seamless scrolling and usability. Last year, Amazon sold specific variants of the Zenbook Pro Duo for a discount of 15% in the run-up to Black Friday. 2. Gaming laptops Gamers need laptops that are responsive, less prone to overheating, and armed with high-end graphics cards. In short, they seek devices that will not leave them high and dry in the middle of a high-octane, graphics-heavy game by being laggy and annoying. Thankfully, several gaming laptops tick these boxes, an example being Lenovo’s IdeaPad Gaming 3. The device has incredible features, such as the latest AMD Ryzen 6000 Series processors, GeForce RTX 30 Series GPUs, and Rapid Charge technology to boost battery by 40% in just 15 minutes. Amazon reduced the price of specific IdeaPad Gaming 3 models by $300 last Black Friday, so gamers can hope for similar savings in 2023. 3. Chromebooks Those who prefer the ultra-reliable Chrome OS can check out Acer’s Chromebook 315. It has a powerful Intel Celeron N4020 dual-core processor, a full HD IPS touchscreen, and over 12 hours of battery life!